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How does it work?

L-ornithine is a non-essential amino acid synthesised in the body by arginine through the urea cycle, and is used supplementally for its role in reducing ammonia concentrations in the blood.1 Excessive exercise causes the accumulation of ammonia which can lead to muscular fatigue, therefore L-ornithine may enhance performance of prolonged exercise and reduce fatigue.2 There are some studies that have shown L-ornithine to also assist in the metabolism of fat and the release of growth hormone, however this is in conjunction with arginine and carnitine.3 L-ornithine is also needed for liver function and immunity.4

What results can be expected?

L-ornithine may assist in reducing muscular fatigue and help improve exercise performance duration, through reducing ammonia concentrations in the blood.5 It may also assist in reducing ammonia in liver diseases such as hepatic encephalopathy.6

1Frank, K. (2014). Supplements. Retrieved Feb 2014, from

2Frank, K. (2014). Supplements. Retrieved Feb 2014, from

3Balch, P. (2006). Prescription for Nutritional Healing. Camberwell: Penguin pp59.

4Balch, P. (2006). Prescription for Nutritional Healing. Camberwell: Penguin pp59.

5Frank, K. (2014). Supplements. Retrieved Feb 2014, from

6Frank, K. (2014). Supplements. Retrieved Feb 2014, from