Hydroxycitric acid (HCA)
How does it work?
HCA is a derivative of citric acid found naturally in the fruit rind of Garcinia spp. and is used as an aid in weight loss and fat reduction.1 Some findings show improved glucose metabolism and leptin-like activity,2 and another study was able to suppress body fat accumulation.3 A meta-analysis of Garcinia concluded that Garcinia extracts/HCA generates weight loss on the short term however more rigorous future trials are needed.4
What results can be expected?
Garcinia/HCA may assist in weight loss, fat reduction and improve glucose metabolism however further rigourous trials are needed to verify these effects.5
1WebMD. (2009). Vitamins and Supplements – Garcinia. Retrieved Jan 2014, from WebMD: http://www.webmd.com/vitamins-supplements/ingredientmono-818-GARCINIA.aspx?activeIngredientId=818&activeIngredientName=GARCINIA
2Hayamizu, K. (2003). Effect of Garcinia cambogia extract on serum leptin and insulin in mice. Fitoterapia, 74(3), 267-73. Retrieved Jan 2014, from http://www.sciencedirect.com/science/article/pii/S0367326X03000364
3Saito, M. (2005). High dose of Garcinia cambogia is effective in suppressing fat accumulation in developing male Zucker obese rats, but highly toxic to the testis. Food and Chemical Toxicology, 43(3), 411-419. Retrieved Jan 2014, from http://www.sciencedirect.com/science/article/pii/S027869150400331X
4Onakpoya, I. (2011). The Use of Garcinia Extract (Hydroxycitric Acid) as a Weight loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials. Journal of Obesity. Retrieved Jan 2014, from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010674/
5WebMD. (2009). Vitamins and Supplements – Garcinia. Retrieved Jan 2014, from WebMD: http://www.webmd.com/vitamins-supplements/ingredientmono-818-GARCINIA.aspx?activeIngredientId=818&activeIngredientName=GARCINIA